April 03, 2023
First, the most common metastasis route of liver cancer is through the portal venous system. The portal vein is the main blood vessel that carries blood from the intestines and basic bile ducts to the liver, and the hepatic portal vein is one of the main branches of the portal vein. When liver cancer invades the portal vein, malignant cells can enter the abdominal cavity through the portal vein and then invade other organs such as the pancreas and stomach.
Secondly, liver cancer can also metastasize through the lymphatic system. The liver has a rich lymphatic system, which is mainly composed of the porta hepatis, the base of the gallbladder, and the lymph nodes next to the hepatic artery trunk. When liver cancer cells invade the lymphatic system, the malignant cells will enter the lymph nodes through lymphatic vessels and then metastasize to other organs such as the abdominal cavity and abdominal aorta lymph nodes.
Third, liver cancer can also metastasize through the peritoneal cavity. The peritoneal cavity refers to the abdominal space surrounded by the peritoneum, a thin membrane covering the intra-abdominal and pelvic cavities. When liver cancer cells invade the peritoneal cavity, the malignant cells can further transfer to the peritoneal wall, small intestine, large intestine and other organs through the fluidity of the peritoneal cavity.
Finally, liver cancer can also metastasize distantly, that is, to organs other than the liver, such as the lungs, bones, brain, etc. This is because the liver is the main metabolic organ of the body and transfers nutrients and drugs absorbed from the intestines throughout the body through the portal venous system. When malignant liver cancer cells invade extrahepatic organs, they can enter other parts through blood circulation or lymph circulation, where they continue to grow and spread.
Generally speaking, liver cancer will eventually metastasize in four directions, namely, portal venous system, lymphatic system, peritoneal cavity and distant metastasis. This metastatic nature makes the treatment of liver cancer relatively complex and difficult. For patients with liver cancer, early detection and early treatment are the keys to improving survival rates. In addition, regular physical examinations and maintaining a healthy lifestyle can also reduce the risk of liver cancer. At the same time, advances in research on the disease and medical technology are expected to provide patients with more treatment options and hope.