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What external treatments are suitable for colorectal cancer

August 15, 2023


The small intestine is the longest segment of the digestive tract, and due to the significant limitations of traditional examination methods in the diagnosis of small intestinal diseases, the diagnostic rate of small intestinal diseases is very low. The emergence of capsule endoscopy has broken through the traditional thinking of mechanical insertion of endoscopes. It can observe small intestinal areas that were previously difficult for endoscopes to reach, with simple operation, no need for sedation, and minimal impact on gastrointestinal motility.

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Since its clinical application was approved by the US FDA in August 2001, capsule endoscopy has become a first-line tool for diagnosing small intestinal diseases.

NCCN:

① An individual with a first-degree relative diagnosed with colorectal cancer at the age of<50 years (or 2 at any age) should undergo colonoscopy starting from the age of 40 years (or the youngest age in the family diagnosed with HNPCC minus 10 years). If the first-degree relative is diagnosed with the disease at the age of<60 years, colonoscopy should be performed every 3-5 years;

② A first-degree relative individual with colorectal cancer should undergo colonoscopy from the age of 40 (or the youngest age in the family diagnosed with HNPCC minus 10 years) and be followed up every 5 years;

③ Individuals with 2 second degree relatives suffering from colorectal cancer have the same screening strategy as ②;

④ Individuals with 1 second degree relative (or any number of third degree relatives) suffering from colorectal cancer have the same screening strategy as ordinary individuals.

In addition, the UK, Canada, and Singapore also have their own screening guidelines. Because the Federal Collaborating Group on Colorectal Cancer is a joint organization composed of the American Society of Gastroenterology (ACG), the American Gastroenterological As association Institute, and ASGE, the guidelines published by the ACG have a wide range of representativeness, and both ASGE and NCCN updated their own guidelines in 2012, so these three were chosen for comparison.

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